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Filed Under (Uncategorized) by admin on 18-11-2008

Vaccine for skin cancer ‘available in five years’

The scientist who developed a vaccine for cervical cancer is working on another inoculation against certain types of skin cancer that could be available in five years time.

Professor Ian Frazer, of the University of Queensland, said tests of the vaccine had proven successful on animals and that human trials could begin next year.

Mr Frazer, who delivered his findings to the Australian Health and Medical Research Congress, said a vaccine for children aged 10 to 12 could be available in five to 10 years.

The jab would protect against squamous cell carcinoma, the second most common skin cancer, but not the more deadly melanomas.

It works by targeting papillomavirus, a common infection which can turn abnormal cells into cancerous cells and is believed to cause at least five per cent of all cancers.

Mr Frazer helped develop the cervical cancer vaccine Gardasil, which is now used to inoculate millions worldwide. He hopes the skin cancer vaccine would work in a similar way.

“What we’ve learnt together, through the study of animal models, is that the skin has natural defences which switch off killer T cells,” he told the conference.

“We’ve also found a number of ways to overcome these blocks and let the immune system work.

“We now want to test vaccines based on this knowledge in clinical trials, to find out whether we can develop vaccines that could be used to treat people at risk of skin cancer.”

Australia suffers from the highest rate of skin cancer in the world, with 1,600 people dying from the disease each year. About 400,000 people are diagnosed with non-melanoma cancers in the county, and 400 people die as a result.

Mr Frazer warned there was still no substitute for staying out of the sun.

skin cancer“In the future, just as the cervical cancer vaccine will complement the cervical cancer screening program, I hope that a skin cancer vaccine will be available to help in the prevention of skin cancer, but we’ll still need to stay out of the sun.”

But cancer specialists have agreed.

Professor Ian Olver of the Australian Cancer Council said that even if the vaccine was proved to work in humans, the normal rules of sun exposure would not change.

“The traditional prevention messages of staying out of the sun during the hottest part of the day, covering up and using sun screen still apply.

“This would be an extra layer of protection.”

Despite it limitations, Mr Olver said the discovery of the vaccine was “a good sign for the future”.

“It is possible other vaccines could flow from this,” he said.



Filed Under (Uncategorized) by admin on 13-04-2008

Acne isn’t “just” a skin problem. In this BBC article, teens can suffer suicidal depression due to low self-esteem. Some of the acne treatments can exacerbate the mood swings resulting in self-destructive behavior.

Depressed about her teenage acne, Melissa Hewett started to self-harm and tried almost monthly to take her own life.

The acne, which covered much of her body, left her feeling worthless and miserable.

She spent time in a mental health clinic getting treatment for her depression.

Now Melissa’s acne has cleared and, at the age of 21, she is starting to live again and is engaged - but she feels acne robbed her of much of her youth.

Self-harming

This summer Melissa is taking part in the British Skin Foundation’s ‘Walk for Skin’ to promote the desperate need for research and funding into acne and its effects.

Indy Rihal, from the foundation, feels the funds are urgently needed.

“Millions of people suffer from skin disease in the UK and more needs to be done to help,” she said.

“The “Walk for Skin” raises money for vital research into all skin diseases, including acne.

“We can make a real difference to those people whose lives are blighted by skin disease and help to fund research into new treatments and eventually cures.”

Melissa is proof of the impact the skin condition can have on young people.

Not only did she struggle to deal with the condition, but her misery was compounded by others simply dismissing it as routine “teenage spots”.

“Having acne was horrible,” said Melissa, an events organiser from Berkshire.

“I developed at a young age, which meant my acne started young at about 11 to 12 years old.

“My back, neck and face were covered in spots. My back was hit worst, so I would always wear a shirt over strappy tops or high-backed tops.”

Melissa was bullied at school and started to cut herself.

“I needed to release pain that was built up, I blamed my skin for causing the problems, so I took it out on my skin,” she said.

“I felt it didn’t matter, as who would ever look at me anyway, except to mock me?”

Taking acne seriously

Melissa tried everything to try to clear her skin, from over-the-counter remedies to prescription drugs, like roaccutane, made by pharmaceutical company Roche.

She was placed on the drug at 13 and she says she feels that combined with anti-depressants, which she was also taking, it triggered her slide from feeling miserable about her acne into a clinical depression.

“I was feeling low because of the acne, but will always think that the anti-depressants and roaccutane triggered me into an actual depression,” she said.

“I felt suicidal, I self-harmed and began not just to feel ugly, but to hate myself.

“I felt worthless, that I wasn’t a good enough human. The treatment did help my skin though.

“But I started to cut myself and attempted suicide every month.

“Once the acne had gone I still found it very difficult to like myself as I had all the scars still from cutting.

“It took a few years and my wonderful fiancé to bring me back up from a very dark place.”

Melissa, who is currently not taking medication, said acne needs to be taken more seriously.

Devastating effects

Dr Alison Layton, consultant dermatologist for the British Skin Foundation, agreed that acne - even quite mild acne - can have devastating affects on self esteem.

Acne facts

  • Acne is the most common inflammatory skin disease in the world
  • It affects between 80-85% of all adolescents. It usually peaks at age 15
  • In 12% of cases acne continues into adulthood - most of these are women

“Although there is a spectrum and you can get very mild and very severe acne, the psychological impact can be quite immense even with quite minimal problems,” she said.

“I think that the reason for that is that it hits young people at a time when they are undergoing the maximum change and wanting to look good.

“People with quite mild acne can get quite depressed by it and yet you can see people with quite severe acne cope quite well.

“The bottom line is that it has the potential to cause problems psychologically.

“The depression can be quite severe, causing suicide, and people can be very clinically depressed.”

Medicines and Healthcare products Regulatory Agency statistics show 27 young people have committed suicide in Britain while taking roaccutane, although there is no proof that the drug is the cause.

A spokesman for Roche said: “Unfortunately, severe acne can cause some sufferers to become depressed and can also affect their mood and self esteem.

“This is why the information provided with roaccutane (isotretinoin) carries a warning that some patients may experience mood changes, including an increase in depression.”

He added that over the past 20 years, more than 13 million people worldwide have been treated for severe acne using roaccutane.

While no causal link had been established between the drug and either depression or suicide, it was constantly monitored.

Talk with your dermatologist and a qualified counselor who specializes in teen self esteem issues.



Filed Under (Uncategorized) by admin on 23-10-2007

If you are looking for a new dermatologist, good sources to ask for referrals are:

  • Family members
  • Friends
  • Co-workers
  • Church or congregation members
  • Your physician
  • Your pharmacist
  • Neighbors

You can also check online dermatologist directories to find out information, addresses and phone numbers of dermatologists.

Be sure to make a list of questions to ask a potential new dermatologist that are important to you.

Some important factors to consider when looking for a new dermatologist might be:

Take your time and write down what is important to you. You also might have to visit several dermatologists before you find one that you are comfortable with, but there is nothing wrong with that.

Recognized dermatological specialties and their definitions include the following, which may help you find the correct dermatologist for your particular need:

  • Acne
  • Actinic Keratosis
  • Albinism
  • Baldness
  • Behcet’s Syndrome
  • Birthmarks
  • Burns
  • Cholesteatoma
  • Dercum Disease
  • Dermatitis Herpetiformis
  • Ectodermal Dysplasia
  • Eczema
  • Epidermolysis Bullosa
  • Erythema Multiforme
  • Gustatory Sweating
  • Hailey-Hailey Disease
  • Hair Loss
  • Head Lice
  • Hidradenitis Suppurativa
  • Hives
  • Hyperhidrosis
  • Lupus
  • Melanoma
  • Nail Patella Syndrome
  • Pemphigoid
  • Pemphigus
  • Poison Ivy
  • Psoriasis
  • Rosacea
  • Scabies
  • Scleroderma
  • Seborrheic Dermatitis
  • Skin Cancer
  • Solar Keratosis
  • Swimmer’s Itch
  • Vitiligo
  • Warts
  • Xanthomas
  • Xeroderma Pigmentosum

Do they perform the treatments you desire?

Acne Photodynamic Treatment | Botox® | Botox® for Hyperhidrosis | Cellulite | Cool Laser | Corevita Health | Cosmelan Depigmentation Treatment | Glycolic Acid Peel | Fat Transfer | Fotofacial / IPL | Fractionated Resurfacing Laser | Hair Loss | Laser Hair Removal | Liposuction | Mesotherapy | Microdermabrasion | Mohs Micrographic Surgery | Minimal Scar Technique | Oxygen Facial | Photodynamic Rejuvenation | Radiance® | Restylane® | Sclerotherapy | Sculptra | Smoothbeam | Stretch Marks | SunFX | TCA Peel | Tattoo Removal | Titan Laser Facelift | V-beam Laser Treatments | Velasmooth

Finding a good dermatologist that you like is important.

It is OK to change dermatologists if you are not happy with your current one.